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A Phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma
Temozolomide is an alkylating agent with activity in the treatment of melanoma metastatic to the brain. Lomustine is a nitrosurea that crosses the blood brain barrier and there is evidence to suggest that temozolomide may reverse resistance to lomustine. A multicentre phase I/II study was conducted...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360201/ https://ncbi.nlm.nih.gov/pubmed/17146474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603503 |
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