A Phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma

Temozolomide is an alkylating agent with activity in the treatment of melanoma metastatic to the brain. Lomustine is a nitrosurea that crosses the blood brain barrier and there is evidence to suggest that temozolomide may reverse resistance to lomustine. A multicentre phase I/II study was conducted...

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Detaylı Bibliyografya
Asıl Yazarlar: Larkin, J M G, Hughes, S A, Beirne, D A, Patel, P M, Gibbens, I M, Bate, S C, Thomas, K, Eisen, T G, Gore, M E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2007
Konular:
Clinical Study
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360201/
https://ncbi.nlm.nih.gov/pubmed/17146474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603503
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