The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice

Retinoids, vitamin A analogues that bind to retinoic acid receptor (RAR) or retinoid X receptor (RXR), play important roles in regulating cell proliferation, apoptosis, and differentiation. Recently, RXR-selective ligands, also referred to as rexinoids, have been investigated as potential chemopreve...

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Detalhes bibliográficos
Main Authors: Li, Y, Zhang, Y, Hill, J, Kim, H-T, Shen, Q, Bissonnette, R P, Lamph, W W, Brown, P H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361704/
https://ncbi.nlm.nih.gov/pubmed/18362934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604320
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