Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles

Acquired drug resistance is a major problem in cancer treatment. To explore the genes involved in chemosensitivity and resistance, 10 human tumour cell lines, including parental cells and resistant subtypes selected for resistance against doxorubicin, melphalan, teniposide and vincristine, were prof...

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Hlavní autoři: Rickardson, L, Fryknäs, M, Dhar, S, Lövborg, H, Gullbo, J, Rydåker, M, Nygren, P, Gustafsson, M G, Larsson, R, Isaksson, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2005
Témata:
Genetics and Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361589/
https://ncbi.nlm.nih.gov/pubmed/16012520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602699
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