Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

To find drugs suitable for repositioning for use against leukemia, samples from patients with chronic lymphocytic, acute myeloid and lymphocytic leukemias as well as peripheral blood mononuclear cells (PBMC) were tested in response to 1266 compounds from the LOPAC(1280) library (Sigma). Twenty-five...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Cancer J
Prif Awduron: Eriksson, A, Österroos, A, Hassan, S, Gullbo, J, Rickardson, L, Jarvius, M, Nygren, P, Fryknäs, M, Höglund, M, Larsson, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450329/
https://ncbi.nlm.nih.gov/pubmed/25885427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.31
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