Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

To find drugs suitable for repositioning for use against leukemia, samples from patients with chronic lymphocytic, acute myeloid and lymphocytic leukemias as well as peripheral blood mononuclear cells (PBMC) were tested in response to 1266 compounds from the LOPAC(1280) library (Sigma). Twenty-five...

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Библиографические подробности
Опубликовано в: :Blood Cancer J
Главные авторы: Eriksson, A, Österroos, A, Hassan, S, Gullbo, J, Rickardson, L, Jarvius, M, Nygren, P, Fryknäs, M, Höglund, M, Larsson, R
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450329/
https://ncbi.nlm.nih.gov/pubmed/25885427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.31
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