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In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
In vitro-based search for promising anti-cancer drug combinations may provide important leads to improved cancer therapies. Currently there are no integrated computational-experimental methods specifically designed to search for combinations, maximizing a predefined therapeutic index (TI) defined in...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585751/ https://ncbi.nlm.nih.gov/pubmed/26392291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14118 |
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