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A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation

There is a need for preclinical models that can enable identification of novel radiosensitizing drugs in clinically relevant high-throughput experiments. We used a new high-throughput compatible total cell kill spheroid assay to study the interaction between drugs and radiation in order to identify...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Karlsson, Henning, Senkowski, Wojciech, Fryknäs, Mårten, Mansoori, Sharmineh, Linder, Stig, Gullbo, Joachim, Larsson, Rolf, Nygren, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731106/
https://ncbi.nlm.nih.gov/pubmed/31523395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27166
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