Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade

Cancers are a heterogeneous mix of cells, some of which exhibit cancer stem cell-like characteristics including ATP-dependent drug efflux and elevated tumorigenic potential. To determine whether aerodigestive squamous cell carcinomas (SCCs) contain a subpopulation of cancer stem cell-like cells, we...

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Main Authors: Loebinger, M R, Giangreco, A, Groot, K R, Prichard, L, Allen, K, Simpson, C, Bazley, L, Navani, N, Tibrewal, S, Davies, D, Janes, S M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2008
主題:
Translational Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361447/
https://ncbi.nlm.nih.gov/pubmed/18219291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604185
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