A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma

BACKGROUND: Cancer stem cells (CSCs) may be postulated mediators of the chemoresistance. This study aimed to determine an effective signal inhibitor with effects on the proliferation of CSCs in combination with anticancer drugs. METHODS: We used three gastric cancer cell lines and three side populat...

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Hlavní autoři: Yashiro, M, Nishii, T, Hasegawa, T, Matsuzaki, T, Morisaki, T, Fukuoka, T, Hirakawa, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833223/
https://ncbi.nlm.nih.gov/pubmed/24129235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.638
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