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TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population

BACKGROUND: Tumours contain stem-like, side population (SP) cells, which have increased tumorigenic potential, resistance to traditional therapies and may be responsible for treatment failures and relapse in patients. METHODS: Mesenchymal stem cells (MSCs) were engineered to express the apoptotic li...

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Detalhes bibliográficos
Main Authors: Loebinger, M R, Sage, E K, Davies, D, Janes, S M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994223/
https://ncbi.nlm.nih.gov/pubmed/21063402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605952
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