Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ

PURPOSE: Tumor-specific delivery of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), an apoptosis-inducing peptide, at effective doses remains challenging. Herein we demonstrate the utility of a scaffold-based delivery system for sustained therapeutic cell release that capitalizes on...

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Main Authors: Reagan, Michaela R., Seib, F. Philipp, McMillin, Douglas W., Sage, Elizabeth K., Mitsiades, Constantine S., Janes, Sam M., Ghobrial, Irene M., Kaplan, David L.
Format: Artigo
Jezik:Inglês
Izdano: Korean Breast Cancer Society 2012
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468780/
https://ncbi.nlm.nih.gov/pubmed/23091539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2012.15.3.273
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