In vitro evolution of horse heart myoglobin to increase peroxidase activity
Random mutagenesis and screening for enzymatic activity has been used to engineer horse heart myoglobin to enhance its intrinsic peroxidase activity. A chemically synthesized gene encoding horse heart myoglobin was subjected to successive cycles of PCR random mutagenesis. The mutated myoglobin gene...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9788999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.12825 |
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