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In vitro evolution of horse heart myoglobin to increase peroxidase activity

Random mutagenesis and screening for enzymatic activity has been used to engineer horse heart myoglobin to enhance its intrinsic peroxidase activity. A chemically synthesized gene encoding horse heart myoglobin was subjected to successive cycles of PCR random mutagenesis. The mutated myoglobin gene...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Wan, Lianglu, Twitchett, Mark B., Eltis, Lindsay D., Mauk, A. Grant, Smith, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1998
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9788999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.12825
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