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In vitro evolution of horse heart myoglobin to increase peroxidase activity

Random mutagenesis and screening for enzymatic activity has been used to engineer horse heart myoglobin to enhance its intrinsic peroxidase activity. A chemically synthesized gene encoding horse heart myoglobin was subjected to successive cycles of PCR random mutagenesis. The mutated myoglobin gene...

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Detalhes bibliográficos
Main Authors: Wan, Lianglu, Twitchett, Mark B., Eltis, Lindsay D., Mauk, A. Grant, Smith, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23613/
https://ncbi.nlm.nih.gov/pubmed/9788999
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