In vitro evolution of horse heart myoglobin to increase peroxidase activity

Random mutagenesis and screening for enzymatic activity has been used to engineer horse heart myoglobin to enhance its intrinsic peroxidase activity. A chemically synthesized gene encoding horse heart myoglobin was subjected to successive cycles of PCR random mutagenesis. The mutated myoglobin gene...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Wan, Lianglu, Twitchett, Mark B., Eltis, Lindsay D., Mauk, A. Grant, Smith, Michael
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1998
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9788999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.12825
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