PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

Rhabdomyosarcoma (RMS) is the most common paediatric soft-tissue sarcoma including two major subtypes, alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS). Increasing evidence suggests that oncogenesis of RMS involves multistages of signalling protein dysregulation which may inclu...

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Bibliografske podrobnosti
Main Authors: Cen, L, Hsieh, F-C, Lin, H-J, Chen, C-S, Qualman, S J, Lin, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360380/
https://ncbi.nlm.nih.gov/pubmed/17848913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603952
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