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PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

Rhabdomyosarcoma (RMS) is the most common paediatric soft-tissue sarcoma including two major subtypes, alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS). Increasing evidence suggests that oncogenesis of RMS involves multistages of signalling protein dysregulation which may inclu...

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書誌詳細
主要な著者: Cen, L, Hsieh, F-C, Lin, H-J, Chen, C-S, Qualman, S J, Lin, J
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360380/
https://ncbi.nlm.nih.gov/pubmed/17848913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603952
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