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2-Deoxyglucose combined with wild type p53 over expression enhances cytotoxicity in human prostate cancer cells via oxidative stress

Over expression of the tumor suppressor gene, wild type p53 (wtp53), using adenoviral vectors (Adp53) has been suggested to kill cancer cells by hydroperoxide-mediated oxidative stress [1, 2] and nutrient distress induced by the glucose analog, 2-deoxyglucose (2DG), has been suggested to enhance tum...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ahmad, Iman M., Abdalla, Maher Y., Aykin-Burns, Nukhet, Simons, Andrean L., Oberley, Larry W., Domann, Frederick E., Spitz, Douglas R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350201/
https://ncbi.nlm.nih.gov/pubmed/18155176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.11.007
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