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Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis

Thirty-four pyrazinamide-resistant and 37 pyrazinamide-susceptible Mycobacterium tuberculosis complex strains were analyzed for pncA gene mutations. None of the sensitive strains had any mutations, apart from silent mutations, whereas all but one resistant strain showed pncA mutations. By using sequ...

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Detalhes bibliográficos
Main Authors: Juréen, Pontus, Werngren, Jim, Toro, Juan-Carlos, Hoffner, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346646/
https://ncbi.nlm.nih.gov/pubmed/18316515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00110-08
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