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Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis

Thirty-four pyrazinamide-resistant and 37 pyrazinamide-susceptible Mycobacterium tuberculosis complex strains were analyzed for pncA gene mutations. None of the sensitive strains had any mutations, apart from silent mutations, whereas all but one resistant strain showed pncA mutations. By using sequ...

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Bibliografiske detaljer
Main Authors: Juréen, Pontus, Werngren, Jim, Toro, Juan-Carlos, Hoffner, Sven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346646/
https://ncbi.nlm.nih.gov/pubmed/18316515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00110-08
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