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Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis

Thirty-four pyrazinamide-resistant and 37 pyrazinamide-susceptible Mycobacterium tuberculosis complex strains were analyzed for pncA gene mutations. None of the sensitive strains had any mutations, apart from silent mutations, whereas all but one resistant strain showed pncA mutations. By using sequ...

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Bibliographische Detailangaben
Hauptverfasser: Juréen, Pontus, Werngren, Jim, Toro, Juan-Carlos, Hoffner, Sven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346646/
https://ncbi.nlm.nih.gov/pubmed/18316515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00110-08
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