MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX(L) and initiates cell death

Activation of the cascade of proteolytic caspases has been identified as the final common pathway of apoptosis in diverse biological systems. We have isolated a gene, termed MRIT, that possesses overall sequence homology to FLICE (MACH), a large prodomain caspase that links the aggregated complex of...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Han, David K. M., Chaudhary, Preet M., Wright, Michael E., Friedman, Cynthia, Trask, Barbara J., Riedel, Rodney T., Baskin, Dale G., Schwartz, Stephen M., Hood, Leroy
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1997
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11333
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