MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX(L) and initiates cell death

Activation of the cascade of proteolytic caspases has been identified as the final common pathway of apoptosis in diverse biological systems. We have isolated a gene, termed MRIT, that possesses overall sequence homology to FLICE (MACH), a large prodomain caspase that links the aggregated complex of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Han, David K. M., Chaudhary, Preet M., Wright, Michael E., Friedman, Cynthia, Trask, Barbara J., Riedel, Rodney T., Baskin, Dale G., Schwartz, Stephen M., Hood, Leroy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11333
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