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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX(L) and initiates cell death

Activation of the cascade of proteolytic caspases has been identified as the final common pathway of apoptosis in diverse biological systems. We have isolated a gene, termed MRIT, that possesses overall sequence homology to FLICE (MACH), a large prodomain caspase that links the aggregated complex of...

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Main Authors: Han, David K. M., Chaudhary, Preet M., Wright, Michael E., Friedman, Cynthia, Trask, Barbara J., Riedel, Rodney T., Baskin, Dale G., Schwartz, Stephen M., Hood, Leroy
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences of the USA 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC23459/
https://ncbi.nlm.nih.gov/pubmed/9326610
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