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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX(L) and initiates cell death

Activation of the cascade of proteolytic caspases has been identified as the final common pathway of apoptosis in diverse biological systems. We have isolated a gene, termed MRIT, that possesses overall sequence homology to FLICE (MACH), a large prodomain caspase that links the aggregated complex of...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Han, David K. M., Chaudhary, Preet M., Wright, Michael E., Friedman, Cynthia, Trask, Barbara J., Riedel, Rodney T., Baskin, Dale G., Schwartz, Stephen M., Hood, Leroy
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326610/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11333
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