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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclX(L) and initiates cell death

Activation of the cascade of proteolytic caspases has been identified as the final common pathway of apoptosis in diverse biological systems. We have isolated a gene, termed MRIT, that possesses overall sequence homology to FLICE (MACH), a large prodomain caspase that links the aggregated complex of...

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Bibliografske podrobnosti
Main Authors: Han, David K. M., Chaudhary, Preet M., Wright, Michael E., Friedman, Cynthia, Trask, Barbara J., Riedel, Rodney T., Baskin, Dale G., Schwartz, Stephen M., Hood, Leroy
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC23459/
https://ncbi.nlm.nih.gov/pubmed/9326610
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