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Protein kinase C and A sites on troponin I regulate myofilament Ca(2+) sensitivity and ATPase activity in the mouse myocardium
Cardiac troponin I (cTnI) is a phosphoprotein subunit of the troponin-tropomyosin complex that is thought to inhibit cardiac muscle contraction during diastole. To investigate the contributions of cTnI phosphorylation to cardiac regulation, transgenic mice were created with the phosphorylation sites...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2343448/ https://ncbi.nlm.nih.gov/pubmed/12923217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.045260 |
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