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Endothelin-1 and photoreleased diacylglycerol increase L-type Ca(2+) current by activation of protein kinase C in rat ventricular myocytes
1. The amphotericin B-perforated whole-cell patch clamp technique was used to determine the modulation of L-type Ca(2+) channels by protein kinase C (PKC)-mediated pathways in adult rat ventricular myocytes. 2. Application of 10 nM endothelin-1 (ET-1) increased peak Ca(2+) current (I(Ca)) by 28·2 ±...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269902/ https://ncbi.nlm.nih.gov/pubmed/10790160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00807.x |
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