Profile of L-type Ca(2+) current and Na(+)/Ca(2+) exchange current during cardiac action potential in ventricular myocytes

OBJECTIVE: The L-type Ca(2+) current (I(Ca,L)) and the Na(+)/Ca(2+) exchange current (I(NCX)) are major inward currents that shape the cardiac action potential (AP). Previously, the profile of these currents during AP was determined from voltage-clamp experiments that used Ca(2+) buffer. In this stu...

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Hauptverfasser: Banyasz, Tamas, Horvath, Balazs, Jian, Zhong, Izu, Leighton T., Chen-Izu, Ye
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252888/
https://ncbi.nlm.nih.gov/pubmed/21884673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2011.08.029
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