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The Inhalation Anesthetic Desflurane Induces Caspase Activation and Increases Amyloid β-Protein Levels under Hypoxic Conditions

Perioperative factors including hypoxia, hypocapnia, and certain anesthetics have been suggested to contribute to Alzheimer disease (AD) neuropathogenesis. Desflurane is one of the most commonly used inhalation anesthetics. However, the effects of desflurane on AD neuropathogenesis have not been pre...

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Autors principals: Zhang, Bin, Dong, Yuanlin, Zhang, Guohua, Moir, Robert D., Xia, Weiming, Yue, Yun, Tian, Ming, Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E., Xie, Zhongcong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335348/
https://ncbi.nlm.nih.gov/pubmed/18326038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800199200
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