A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

The c-myb promoter contains multiple GGA repeats beginning 17 bp downstream of the transcription initiation site. GGA repeats have been previously shown to form unusual DNA structures in solution. Results from chemical footprinting, circular dichroism and RNA and DNA polymerase arrest assays on olig...

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Hlavní autoři: Palumbo, SunMi L., Memmott, Regan M., Uribe, Diana J., Krotova-Khan, Yulia, Hurley, Laurence H., Ebbinghaus, Scot W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330228/
https://ncbi.nlm.nih.gov/pubmed/18252774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1069
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