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NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region
BCL2 protein functions as an inhibitor of cell apoptosis and has been found to be aberrantly expressed in a wide range of human diseases. A highly GC-rich region upstream of the P1 promoter plays an important role in the transcriptional regulation of BCL2. Here we report the NMR solution structure o...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636422/ https://ncbi.nlm.nih.gov/pubmed/16998187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl610 |
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