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Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses
G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter. Folding of HIV-1 LTR G4s inhibits viral transcription; stabilization by G4 lig...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435695/ https://ncbi.nlm.nih.gov/pubmed/28515481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02291-1 |
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