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Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
Fibrillar protein deposits (amyloid) in the pancreatic islets of Langerhans are thought to be involved in death of the insulin-producing islet β cells in type 2 diabetes mellitus. It has been suggested that the mechanism of this β cell death involves membrane disruption by human islet amyloid polype...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329711/ https://ncbi.nlm.nih.gov/pubmed/18408164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708354105 |
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