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Biophysical Investigation of the Membrane-Disrupting Mechanism of the Antimicrobial and Amyloid-Like Peptide Dermaseptin S9

Dermaseptin S9 (Drs S9) is an atypical cationic antimicrobial peptide with a long hydrophobic core and with a propensity to form amyloid-like fibrils. Here we investigated its membrane interaction using a variety of biophysical techniques. Rather surprisingly, we found that Drs S9 induces efficient...

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Detalhes bibliográficos
Main Authors: Caillon, Lucie, Killian, J. Antoinette, Lequin, Olivier, Khemtémourian, Lucie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795727/
https://ncbi.nlm.nih.gov/pubmed/24146759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075528
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