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The role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes
Human islet amyloid polypeptide (hIAPP) forms amyloid fibrils in pancreatic islets of patients with type 2 diabetes mellitus. It has been suggested that the N-terminal part, which contains a conserved intramolecular disulfide bond between residues 2 and 7, interacts with membranes, ultimately leadin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903700/ https://ncbi.nlm.nih.gov/pubmed/20052582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-009-0572-4 |
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