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Structure and dynamics of de novo proteins from a designed superfamily of 4-helix bundles

Libraries of de novo proteins provide an opportunity to explore the structural and functional potential of biological molecules that have not been biased by billions of years of evolutionary selection. Given the enormity of sequence space, a rational approach to library design is likely to yield a h...

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Hlavní autoři: Go, Abigail, Kim, Seho, Baum, Jean, Hecht, Michael H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327279/
https://ncbi.nlm.nih.gov/pubmed/18436954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073377908
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