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Solution structure of a de novo protein from a designed combinatorial library

Combinatorial libraries of de novo amino acid sequences can provide a rich source of diversity for the discovery of novel proteins. Randomly generated sequences, however, rarely fold into well ordered protein-like structures. To enhance the quality of a library, diversity must be focused into those...

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Detalhes bibliográficos
Main Authors: Wei, Yinan, Kim, Seho, Fela, David, Baum, Jean, Hecht, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC263778/
https://ncbi.nlm.nih.gov/pubmed/14593201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835644100
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