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Solution structure of a de novo protein from a designed combinatorial library

Combinatorial libraries of de novo amino acid sequences can provide a rich source of diversity for the discovery of novel proteins. Randomly generated sequences, however, rarely fold into well ordered protein-like structures. To enhance the quality of a library, diversity must be focused into those...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Wei, Yinan, Kim, Seho, Fela, David, Baum, Jean, Hecht, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC263778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14593201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1835644100
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