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Library analysis of SCHEMA-guided protein recombination

The computational algorithm SCHEMA was developed to estimate the disruption caused when amino acid residues that interact in the three-dimensional structure of a protein are inherited from different parents upon recombination. To evaluate how well SCHEMA predicts disruption, we have shuffled the dis...

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Main Authors: Meyer, Michelle M., Silberg, Jonathan J., Voigt, Christopher A., Endelman, Jeffrey B., Mayo, Stephen L., Wang, Zhen-Gang, Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323955/
https://ncbi.nlm.nih.gov/pubmed/12876318
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