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On the conservative nature of intragenic recombination

Intragenic recombination rapidly creates protein sequence diversity compared with random mutation, but little is known about the relative effects of recombination and mutation on protein function. Here, we compare recombination of the distantly related β-lactamases PSE-4 and TEM-1 to mutation of PSE...

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Detalhes bibliográficos
Main Authors: Drummond, D. Allan, Silberg, Jonathan J., Meyer, Michelle M., Wilke, Claus O., Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556249/
https://ncbi.nlm.nih.gov/pubmed/15809422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500729102
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