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On the conservative nature of intragenic recombination

Intragenic recombination rapidly creates protein sequence diversity compared with random mutation, but little is known about the relative effects of recombination and mutation on protein function. Here, we compare recombination of the distantly related β-lactamases PSE-4 and TEM-1 to mutation of PSE...

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Détails bibliographiques
Auteurs principaux: Drummond, D. Allan, Silberg, Jonathan J., Meyer, Michelle M., Wilke, Claus O., Arnold, Frances H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC556249/
https://ncbi.nlm.nih.gov/pubmed/15809422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500729102
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