Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling.
Activation of the Raf serine/threonine protein kinases is tightly regulated by multiple phosphorylation events. Phosphorylation of either tyrosine 340 or 341 in the catalytic domain of Raf-1 has been previously shown to induce the ability of the protein kinase to phosphorylate MEK. By using a combin...
Shranjeno v:
| izdano v: | Mol Cell Biol |
|---|---|
| Principais autores: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1997
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4509 |
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