Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling.

類似資料

• Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation.
  著者:: Mason, C S, 等
  出版事項: (1999)
• Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues.
  著者:: Chuang, E, 等
  出版事項: (1994)
• Characterization of Ser(338) Phosphorylation for Raf-1 Activation
  著者:: Zang, Mengwei, 等
  出版事項: (2008)
• Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation.
  著者:: Marais, R, 等
  出版事項: (1995)
• An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ.
  著者:: Luo, Z, 等
  出版事項: (1997)