Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling.

Activation of the Raf serine/threonine protein kinases is tightly regulated by multiple phosphorylation events. Phosphorylation of either tyrosine 340 or 341 in the catalytic domain of Raf-1 has been previously shown to induce the ability of the protein kinase to phosphorylate MEK. By using a combin...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Diaz, B, Barnard, D, Filson, A, MacDonald, S, King, A, Marshall, M
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 1997
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4509
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