Cell transformation mediated by homodimeric E2A-HLF transcription factors.
The E2A-HLF fusion gene, created by the t(17;19)(q22;p13) chromosomal translocation in pro-B lymphocytes, encodes an oncogenic protein in which the E2A trans-activation domain is linked to the DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF), a member of the proline- and...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1417 |
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