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Cell transformation mediated by homodimeric E2A-HLF transcription factors.

The E2A-HLF fusion gene, created by the t(17;19)(q22;p13) chromosomal translocation in pro-B lymphocytes, encodes an oncogenic protein in which the E2A trans-activation domain is linked to the DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF), a member of the proline- and...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Inukai, T, Inaba, T, Yoshihara, T, Look, A T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032268/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1417
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