The AD1 and AD2 Transactivation Domains of E2A Are Essential for the Antiapoptotic Activity of the Chimeric Oncoprotein E2A-HLF

The chimeric oncoprotein E2A-HLF, generated by the t(17;19) chromosomal translocation in pro-B-cell acute lymphoblastic leukemia, incorporates the transactivation domains of E2A and the basic leucine zipper (bZIP) DNA-binding and protein dimerization domain of HLF (hepatic leukemic factor). The abil...

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Autors principals: Inukai, Takeshi, Inaba, Toshiya, Ikushima, Satoshi, Look, A. Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109189/
https://ncbi.nlm.nih.gov/pubmed/9742120
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