The AD1 and AD2 Transactivation Domains of E2A Are Essential for the Antiapoptotic Activity of the Chimeric Oncoprotein E2A-HLF

The chimeric oncoprotein E2A-HLF, generated by the t(17;19) chromosomal translocation in pro-B-cell acute lymphoblastic leukemia, incorporates the transactivation domains of E2A and the basic leucine zipper (bZIP) DNA-binding and protein dimerization domain of HLF (hepatic leukemic factor). The abil...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Inukai, Takeshi, Inaba, Toshiya, Ikushima, Satoshi, Look, A. Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.6035
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