Cell transformation mediated by homodimeric E2A-HLF transcription factors.

The E2A-HLF fusion gene, created by the t(17;19)(q22;p13) chromosomal translocation in pro-B lymphocytes, encodes an oncogenic protein in which the E2A trans-activation domain is linked to the DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF), a member of the proline- and...

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Bibliographic Details
Main Authors: Inukai, T, Inaba, T, Yoshihara, T, Look, A T
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC231866/
https://ncbi.nlm.nih.gov/pubmed/9032268
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