The E2A-HLF Oncoprotein Activates Groucho-Related Genes and Suppresses Runx1

The E2A-HLF fusion gene, formed by the t(17;19)(q22;p13) chromosomal translocation in leukemic pro-B cells, encodes a chimeric transcription factor consisting of the transactivation domain of E2A linked to the bZIP DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF). This on...

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Hlavní autoři: Dang, Jinjun, Inukai, Takeshi, Kurosawa, Hidemitsu, Goi, Kumiko, Inaba, Toshiya, Lenny, Noel T., Downing, James R., Stifani, Stefano, Look, A. Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87312/
https://ncbi.nlm.nih.gov/pubmed/11486032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5935-5945.2001
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