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The E2A-HLF Oncoprotein Activates Groucho-Related Genes and Suppresses Runx1
The E2A-HLF fusion gene, formed by the t(17;19)(q22;p13) chromosomal translocation in leukemic pro-B cells, encodes a chimeric transcription factor consisting of the transactivation domain of E2A linked to the bZIP DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF). This on...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87312/ https://ncbi.nlm.nih.gov/pubmed/11486032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5935-5945.2001 |
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