The E2A-HLF Oncoprotein Activates Groucho-Related Genes and Suppresses Runx1

The E2A-HLF fusion gene, formed by the t(17;19)(q22;p13) chromosomal translocation in leukemic pro-B cells, encodes a chimeric transcription factor consisting of the transactivation domain of E2A linked to the bZIP DNA-binding and protein dimerization domain of hepatic leukemia factor (HLF). This on...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dang, Jinjun, Inukai, Takeshi, Kurosawa, Hidemitsu, Goi, Kumiko, Inaba, Toshiya, Lenny, Noel T., Downing, James R., Stifani, Stefano, Look, A. Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11486032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.17.5935-5945.2001
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